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目的探讨稳定期慢性阻塞性肺疾病(COPD)患者贫血的发生率和影响因素。方法对96例稳定期COPD患者检测血常规、C反应蛋白(CRP)、白蛋白(ALB)、肺功能(FEV1%预计值)、呼吸困难分级、过去1年因急性加重而住院≥2次的人数、身高和体重、计算体质指数(BMI)。根据血红蛋白浓度(Hb)分为贫血组和非贫血组,比较两组间年龄、CRP、BMI、ALB、FEV1%、mMRC、去年1年因急性加重而住院≥2次的住院人数比例有无统计学差异。结果贫血组12例,非贫血组84例,贫血发生率12.5%;贫血组平均年龄、CRP、mMRC、去年1年因急性加重而住院≥2次的住院人数比例高于非贫血组(<0.05);ALB、BMI低于非贫血组(<0.05);两组FEV1%无统计学差异(跃0.05)。结论稳定期COPD患者并发贫血并不少见,系统性炎症和营养不良可导致贫血。“,”Objective To explore the incidence of anemia and its relevant factors in stable chronic obstructive pulmonary disease (COPD).Methods Ninty-six patients with stable COPD were enrol ed. Routine blood test,C-reactive protein(CRP) ,albumin,pulmonary function(FEV1pre),body mass index,dyspnea with the Modified British Medical Research Council(mMRC),the patients with two or more exacerbation in the preceding year were measured or calculated. Al patients were divided into two groups based on whether anemia existed,and patient's age,CRP,ALB,FEV1 pre, mMRC,BMI,the ratio of hospitalization due to two or more exacerbation in the preceding year were analyzed.Results Twelve cases were anemia group and the incidence of anemia was 12.5%.The degree of anemia group cor elated with patient's age,CRP, mMRC, and the ratio of hospitalization due to two or more exacerbation in the preceding year was higher than non-anemia group ( <0.05),and the level of ALB,BMI was lower than non-anemia group ( 0.05).Conclusion The prevalence of anemia is not rare in stable COPD, inflammation and malnutrition is associated with anemia.