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应用前列腺素 E_2(简称 PGE_2)阴道栓剂引产具有简单、无害、引产成功率较高的优点。但有产生子宫收缩过强的缺点,主要发生在高剂量组。作者观察到应用 PGE_23mg 组有1例引产前宫口开4cm的经产妇发生了宫缩过强,同时也注意到引产前宫颈条件相对不成熟时和既使在引产前用 PGE_2栓促使宫颈成熟时,也能发生。Tromans 等人观察到两例在放入4mgPGE_2栓后胎心率很快减慢,有1例情况严重而需要行急症剖腹产。Liggins 应用shepherd 等人所用 PGE_2剂量的1/10,即反复给
Application of prostaglandin E_2 (referred to as PGE_2) vaginal suppository induction is simple, harmless, the advantages of high success rate of induction. However, there is the disadvantage of producing uterine contractions, mainly in the high-dose group. The authors observed that the application of PGE_23mg group, 1 case of prenatal cervix open 4cm before the occurrence of uterine contractions too strong, but also noted that pre-induction of cervical conditions are relatively immature and even in the pre-labor with PGE_2 suppository to promote cervical ripening It can happen too. In two cases, Tromans et al observed that the fetal heart rate slowed down rapidly after 4 mg of PGE 2 suppositories were inserted, one of which was severe and required an emergency c-section. Liggins application Shepherd et al PGE_2 dose 1/10, which is repeated to give