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抗菌肽是一类广泛存在于整个生物界中的双亲性小分子碱性多肽,是生物体固有免疫的关键因子之一[1]。自Steiner等[2]在天蚕(Hyaophora cecro-pia)中发现世界上第一个抗菌肽—天蚕素(Cecropin)后,到目前为止,在各种生物中总共发现了1 200多种抗菌肽。由于这类多肽通常具有广谱高
Antimicrobial peptides are a kind of amphipathic small molecule alkaline peptides that are widely found in the entire biological world and are one of the key factors in innate immunity of organisms [1]. Since Steiner et al [2] discovered the world’s first antimicrobial peptide Cecropin in Hyaophora cecro-pia, a total of over 1,200 antimicrobial peptides have been found in various organisms so far. Because of the broad spectrum of such polypeptides