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(1)高度特异性追踪单克隆抗体(McAb)已在医学中取得成效,本文介绍了这种免疫防御武器的应用可能性和限度。Kohler应用细胞杂交瘤技术,将致敏的B淋巴细胞与骨髓瘤细胞融合形成杂交瘤细胞,可按照人们的意愿生产大量纯的McAb。Kohler和Milstein由于发展了生产McAb的技术于1984年获诺贝尔医学奖金。目前McAb已广泛应用于医学领域。
(1) The highly specific tracking of monoclonal antibodies (McAbs) has achieved success in medicine. This article describes the possibilities and limits of the application of such immune defensive weapons. Kohler uses the technique of cell hybridoma to fuse sensitized B lymphocytes with myeloma cells to produce hybridoma cells, producing large quantities of pure McAb as often as desired. Kohler and Milstein won the Nobel Prize in Medicine in 1984 for developing McAb technology. McAb has been widely used in medicine.