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对1991年10月～1993年3月在东京34所医院就诊,准备每隔3～4周反复进行同一化疗,并在开始化疗后的对照观察期白细胞数降至2000/mm~3以下的卵巢痛患者共65例使用G-CSF(granulocyte-colony stimulating factor),以观察治疗白细胞减少的疗效。除外以下病例:化疗同时行放疗者;对照观察期前3周行化疗及放疗者;对照观察期的化疗前白细胞在3000/mm~3以下,血小板在10×10~4/mm~3以下,血红蛋白在9g/dl以下,GOT、GPT为,正常值的2倍以下,血清肌酸酐在正常范围(1.5mg/dl)以仁以及有严重合并症或有药物过敏史的病例。
From October 1991 to March 1993, patients were treated in 34 hospitals in Tokyo. The same chemotherapy was repeated every 3 to 4 weeks and the number of white blood cells dropped below 2000 / mm 3 in the control observation period after chemotherapy A total of 65 patients with pain using granulocyte-colony stimulating factor G-CSF to observe the treatment of leukopenia. In addition to the following cases: chemotherapy at the same time radiotherapy; control observation period before 3 weeks of chemotherapy and radiotherapy; control observation period of pre-chemotherapy leukocytes in 3000 / mm ~ 3 below, platelets in 10 * 10 ~ 4 / mm ~ Hemoglobin in 9g / dl or less, GOT, GPT, less than 2 times the normal, serum creatinine in the normal range (1.5mg / dl) of Ren and serious complications or drug allergy history.