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血吸虫病在世界大片土地上已流行很久。血吸虫有好几种,其中主要的有流行在非洲和中南美洲的曼氏及埃及血吸虫,以及流行在亚洲东南部的日本血吸虫。欧美各国对曼氏血吸虫病曾有广泛的研究,许多经过试验的药物中以锑的有机化合物疗效较好。这些化合物大多是羟基酸、酚或硫醇的锑衍生物,其中最著名的药物有酒石酸锑钾(钠)(Ⅰ)及福锑(Fouadin)(Ⅱ)。此外,非金属化合物报导有效的有硫蒽酮(Thioxan-thone)及二氨二苯氧烷(p,p’-Diaminodi-phenoxyalkanes)两种类型。
Schistosomiasis has long been popular in large areas of the world. Schistosoma there are several, including the main popular in Africa and Central South America’s Manchurian and Schistosoma, and the prevalence of Schistosoma japonicum in southeastern Asia. Many countries in Europe and the United States have conducted extensive research on Schistosoma mansoni and many of the tested compounds have better antimony organic compounds. These compounds are mostly antimony derivatives of hydroxy acids, phenols or mercaptans. The best known of these are antimony potassium tartrate (Na) (I) and Fouadin (II). In addition, non-metallic compounds reported effective Thioxanthone (Thioxan-thone) and diamino diphenoxane (p, p’-Diaminodi-phenoxyalkanes) two types.