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通过高效液相色谱分析技术建立抗纤复方药物血清质量控制指标.方法 :采用反相高效液相色谱法 ,同时测定抗纤复方原液及其血清中君药丹参的 4种有效成分.结果 :丹参素与丹酚酸B的特征峰在抗纤复方原液及其药物血清中均能够清楚地再现.结论 :丹参素和丹酚酸B可作为抗纤复方药物血清的质控指标.“,”Objetve:To establish the qulity markers on the drug sera of anti-fibrosis compond priscription(ACP) by high performance liquid chromatography (HPLC).Methods:By a RP-HPLC method,four Danshen ingredients in the ACP solution and the rat sera were determined.Results:The HPLC peaks of Danshensu and Lithospermate B in the ACP solution and the rat serum were reproducible clearly.Conclusion:Danshensu and Lithospermate B could be regarded as useful markers to monitor the drug sera of ACP.