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用低晒的克山病病区粮喂养大鼠并补充不同剂量的硒，观察了硒对心肌甲状腺激素（ＴＨ）代谢调节作用的影响。结果表明，低晒饲料组血清和心肌谷胱甘肽过氧化物酶（ＧＳＨ－Ｐｘ）活性；心肌Ｔ４５’－脱单碘酶活性；心肌线粒体α－磷酸甘油脱氢酶（α－ＧＰｕ）活性均明显低于富硒的非病区和常备饲料组。血及心肌脂质过氧化物（ＬＰＯ）含量则相反。在单纯补硒后上述指标均有明显改善。表明晒在心肌甲状腺激素代谢调节作用中起着重要作用。
Rats in low Keshan disease were fed with different doses of selenium to observe the effects of selenium on myocardial thyroid hormone (TH) metabolism. The results showed that the activity of glutathione peroxidase (GSH-Px) in serum and myocardium of low-sun-fed group was higher than that of control group (P <0.05). The activity of cardiac T45’-deaminase and the activity of myocardial mitochondrial α-GPu Were significantly lower than the non-selenium-rich areas and standing feed group. Blood and myocardial lipid peroxides (LPO) content is the opposite. In pure selenium after the above indicators have significantly improved. It shows that sun plays an important role in myocardial thyroid hormone metabolism regulation.