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近年来,维生素A的防癌抗癌作用引起了人们极大的兴趣.大大促进了维生素A代谢的基础研究,进展很快.其中,对肝脏在维生素A代谢中的作用也有了更新、更多、更深入的了解. 肝脏与维生素A的摄取肝脏通过分泌胆汁酸盐增强小肠内视黄醇酯被酯酶水解,形成微胶粒而被小肠粘膜细胞摄取,在微粒体酶——酰基辅酶A视黄醇酰基转移酶(acyl-CoA:retinol acyltransferase)的作用下,视黄醇重新酯
In recent years, the anti-cancer anti-cancer effect of vitamin A aroused great interest in people greatly promoted the basic research of vitamin A metabolism, and progressed rapidly.Among them, the role of liver in vitamin A metabolism has also been updated, more , More in-depth understanding of the liver and vitamin A uptake of the liver through the secretion of bile salts enhance the small intestine retinol ester esterase hydrolysis, the formation of micelles and uptake by small intestinal mucosal cells in the microsomal enzyme - acyl-CoA Under the action of acyl-CoA: retinol acyltransferase,