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A model on the earthquake effects combination in wind resistant design of high-rise flexible structures is proposed in accordance with the probability method. Based on the Turkstra criteria, the stochastic characters of wind velocity, earthquake ground acceleration and excitations occurrence probability are taken into account and then the combination of the earthquake effects in structure wind resistant design is analyzed with the convolution approach. The results indicate that as for the tall flexible buildings whose lateral force is governed by wind loading, the maximum lateral loads verification with respect to the wind resistant design combined with earthquake effects may be more unfavorable compared with that in terms of the earthquake resistant design involving wind effects.