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局部应用溶栓酶治疗肺血栓栓塞尚有争议。特别是有关适应症的选择、剂量的大小、疗程及用药方式尚无定论。经肺血管造影证实,对肺血栓栓塞的治疗,静滴尿激酶12小时其效果较静滴肝素为佳。 Gttingen医院以链激酶经血管造影导管直接注入急性肺大块血栓栓塞患者的血流,临床疗效良好。本文探讨对急性肺大块血栓栓塞病例局部注射尿激酶数天后的临床及血流动力学效应。病例中男8、女4例,平均年龄47岁。全部均因心慌、胸痛、呼吸困难、冷汗等进行性加剧而急诊入院。其中1例有心源性休克。根据临床表现、ECG变化及动脉血气分析拟诊肺血栓栓塞。12例诊断均已证
Topical thrombolytic therapy of pulmonary thromboembolism is still controversial. In particular, the choice of indications, the size of the dose, the course of treatment and the mode of administration is inconclusive. Confirmed by pulmonary angiography, the treatment of pulmonary thromboembolism, intravenous infusion of urokinase 12 hours more effective than intravenous drip of heparin. Gttingen hospital with streptokinase angiography catheter directly into patients with acute pulmonary thromboembolism in the blood flow, clinical efficacy is good. This article explores the clinical and hemodynamic effects of local injection of urokinase in acute pulmonary thromboembolism patients for several days. Cases of male 8, female 4 cases, the average age of 47 years old. All were due to palpitation, chest pain, difficulty breathing, cold sweat and other sexual exacerbations and emergency admission. One case of cardiogenic shock. Pulmonary thromboembolism was proposed based on clinical manifestations, ECG changes and arterial blood gas analysis. All 12 cases have been diagnosed