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本文对静脉注射免疫球蛋白治疗难治性特发性炎性结肠疾病的效果及安全性进行了小样本试验。选择经免疫抑制剂或外科治疗无效的12例难治性特发性结肠炎(溃疡性结肠炎9例、克隆氏病3例)作为观察对象。其中11例经激素等多种治疗后结肠镜检仍有中、重度粘膜炎性反应,症状持续6个月以上,1例呈激素依赖;10例呈广泛性结肠炎,其中全绒肠炎6例,炎性反应延及横结肠或结肠肝曲4例。9例需住院治疗。首先给予1～2次诱导治疗,即在
In this paper, we performed a small sample test on the efficacy and safety of intravenous immunoglobulin in the treatment of refractory idiopathic inflammatory colon diseases. Twelve patients with refractory idiopathic colitis (ulcerative colitis 9 and Crohn’s disease 3) immunosuppressed or surgically ineffective were selected as the observation subjects. Among them, there were still 11 cases of moderate and severe mucosal inflammatory reaction in colonoscopy after hormone therapy and other treatments. The symptoms persisted for more than 6 months, and one case was hormone-dependent. The other 10 cases were extensive colitis, of which 6 cases , Inflammatory reaction extended to transverse colon or colon liver song in 4 cases. Nine patients needed hospitalization. First give 1 or 2 induction therapy, that is