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目的 分析长期规律口服抗精神病药物患者的血液生化指标变化情况.方法 选取2019年1月～2020年12月在本院治疗的56例精神类疾病患者作为研究对象,同期选择56例健康人员,对比长期口服抗精神病药物患者与正常人群的血液生化指标变化情况,包括谷丙转氨酶(Alanine transaminase,ALT)、谷草转氨酶(aspartate transaminase,AST)、血清总蛋白(total protein,TP)、白蛋白(albumin,ALB).结果 通过观察发现,长期规律口服抗精神病药物患者的血液生化指标显著高于正常人体指标(P ＜ 0.05).结论 长期规律口服抗精神病药物能够大幅度降低患者体内的血液生化指标.“,”Objective To analyze the changes of blood biochemical indexes in patients with long-term regular oral antipsychotics. Methods We selected 56 patients with mental illnesses treated in our hospital from January 2019 to December 2020 as the research objects. During the same period, we selected 56 healthy people and compared them with the blood biochemical index of the normal population: Alanine transaminase (Alanine transaminase) ALT, aspartate transaminase (AST), total protein (TP), albumin (ALB) changes were compared. Results Through observation, the blood biochemical indexes of patients with long-term regular oral antipsychotics were significantly higher than those of normal people (P＜0.05). Conclusion Long-term regular oral antipsychotics can greatly affect the blood biochemical indexes in patients.