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【目的】通过研究辅助受孕儿24月龄时的精神运动发育水平,以评价辅助生殖技术的安全性。【方法】采用前瞻性对照研究方法,实验组为人工辅助受孕妊娠儿,对照组为自然受孕妊娠儿,将两组人群在母亲年龄、产次、家庭社会阶层、双亲受教育程度等几个方面进行配对,均自母亲孕28周起入组登记定期随访收集相关资料并由经过培训的指定专业人员采用CDCC婴幼儿发育量表定期对其行精神运动发育评估至24月龄,获得智力发育指数及运动发育指数。【结果】辅助受孕儿童至24月龄时其精神运动发育水平与自然受孕儿童相比差异无统计学意义(P>0.05)。【结论】辅助受孕儿童24月龄时的精神运动发育水平正常,初步证明我国目前的辅助生殖技术是安全的。
【Objective】 To evaluate the safety of assisted reproductive technology by studying the level of psychomotor development during 24-month-old assisted conception. 【Methods】 A prospective and controlled study was conducted. The experimental group was an artificial assisted pregnancy and the control group was a spontaneous pregnancy. The two groups were divided into three groups: mother’s age, parity, family’s social class and parents’ education level Were paired, from the mother 28 weeks of pregnancy into the group registration regular follow-up to collect relevant information by the designated professional training of the CDCC using the CDDF scale development of their mental activity on a regular basis to 24 months of age, access to mental development index And sports development index. 【Results】 There was no significant difference in mental development between children with conception at 24 months of gestation and children with conception at birth (P> 0.05). 【Conclusion】 The level of psychomotor development at 24 months of assisted conception children is normal, which proves that our current assisted reproductive technology is safe.