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放射外科适于直径<3cm的单发或多发脑转移瘤的治疗,可控制症状、提高生存质量、延长生存时间,具有与手术联合全脑放疗相当的疗效,对于重要功能区域病灶具有明显优势,联合立体定向穿刺可治疗体积较大的囊性转移瘤;联合全脑放疗可减少新生肿瘤,但不能提高生活质量、延长生存期。目前认为放射外科应根据病灶体积和数目调整处方剂量,70%等剂量曲线14Gy的处方剂量可降低副作用,而疗效无明显下降,治疗后死亡原因多数为原发肿瘤或系统疾病恶化。
Radiological surgery for the treatment of single or multiple brain metastases <3cm in diameter, can control the symptoms, improve the quality of life and prolong the survival time, has the same efficacy as surgery combined with whole brain radiotherapy, has obvious advantages for the lesions of important functional areas, Joint stereotactic puncture can treat bulky cystic metastases; combined with whole brain radiotherapy can reduce the new tumor, but can not improve the quality of life and prolong survival. At present, radiosurgery should be based on the volume and number of lesions to adjust the prescription dose, 70% isodose dose 14Gy prescription dose can reduce the side effects, but no significant reduction in efficacy, the majority of deaths after treatment of primary tumor or systemic disease worsened.