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近年来,急性心肌梗塞(AMI)合并泵衰竭已成为心脏性死亡的主要原因。目前的注意力已转向预防心室衰竭,限制心肌梗塞范围乃至于防止心肌梗塞形成。采用溶栓治疗以期及早恢复心肌灌流,已重新引起人们的特别重视。AMI时所缺乏的最关键的基质是氧,早期再灌注以重建血供和恢复供氧,代表着最有前途的缩小梗塞范围的方法。
In recent years, acute myocardial infarction (AMI) with pump failure has become the leading cause of cardiac death. Current attention has shifted to preventing ventricular failure, limiting myocardial infarct size and preventing myocardial infarction. The use of thrombolytic therapy in order to resume myocardial perfusion earlier, has re-attracted people’s special attention. The most critical substrates that are lacking in AMI are oxygen. Early reperfusion to reconstruct blood supply and restore oxygen supply represents the most promising way to reduce infarct size.