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目的:探讨原发性肝细胞癌(肝癌)治疗中应用实时超声导航的解剖性肝段切除的疗效。方法:回顾2014年6月—2015年6月安徽医科大学附属安徽省立医院30例行实时超声导航下解剖性肝段切除的肝癌患者(观察组)与30例行非解剖性肝段切除的肝癌患者(对照组)临床资料,比较两组患者相关临床指标。结果:两组患者术前一般资料具有可比性。与对照组比较,观察组手术时间延长(153.5 min vs.128.5 min,P<0.05),术中出血量无统计学差异(175.0 m L vs.200.00 m L,P>0.05),但术中输血率降低(10.0%vs.36.7%,P<0.05)、肝门阻断率降低(16.7%vs.40.0%,P<0.05);两组并发症发生率无统计学差异(13.3%vs.33.3%,P>0.05);观察组的1年复发率低于对照组(16.7%vs.43.3%,P<0.05),1年存活率高于对照组(80.0%vs.53.3%,P<0.05)。结论:实时超声导航下解剖性肝段切除的应用对减少肝癌患者术后肿瘤的复发、改善预后有着积极的作用。
Objective: To investigate the efficacy of anatomic segmentectomy using real-time ultrasound guidance in the treatment of primary hepatocellular carcinoma (HCC). Methods: From June 2014 to June 2015, 30 patients with liver cancer undergoing real-time ultrasound-guided liver resection (observation group) and 30 patients undergoing non-anatomic segmentectomy Liver cancer patients (control group) clinical data, the relative clinical indicators of two groups were compared. Results: The preoperative general information of two groups of patients was comparable. Compared with the control group, the operation time in the observation group was prolonged (153.5 min vs.128.5 min, P <0.05), and there was no significant difference in blood loss between the two groups (175.0 m L vs.200.00 m L, P> 0.05) (10.0% vs.36.7%, P <0.05), hepatic portal blockage rate decreased (16.7% vs.40.0%, P <0.05), and there was no significant difference in the incidence of complications between the two groups (13.3% vs.33.3 %, P> 0.05). The 1-year recurrence rate of the observation group was lower than that of the control group (16.7% vs.43.3%, P <0.05), and the 1-year survival rate was higher than that of the control group (80.0% vs.53.3% ). Conclusion: The application of real-time ultrasound guided anatomical segmentectomy has a positive effect on reducing the recurrence and prognosis of patients with liver cancer after operation.