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众所周知,人绒毛膜促性腺激素(hCG)是妊娠期由胎盘大量分泌的一种糖蛋白激素。但近年来有报告指出,滋养叶及非滋养叶肿瘤、细菌以及人体正常组织均能合成类hCG物质。本文用实验资料说明非妊娠及良性病患者血中有无这种激素;恶性肿瘤患者的hCG是否高于良性病患者;肿瘤患者的hCG水平对手术、化疗及放疗等各种治疗的敏感性;以及能否证明hCG的非妊娠性及非肿瘤性来源的假说。材料与方法:血清标本取自18例宫内膜癌、17例卵巢腺癌及34例妇科良性病患者(包括子宫肌瘤及卵巢囊肿等);腹水标本取自9例卵巢癌患者;卵巢囊肿液取自14例良性卵巢囊肿。此外,30个人垂体取自无肿瘤的非妊娠对象。
It is well known that human chorionic gonadotropin (hCG) is a glycoprotein hormone secreted by the placenta during pregnancy. However, in recent years, it has been reported that hCG-like substances can be synthesized in trophoblastic and non-trophoblastic tumors, bacteria and normal human tissues. In this paper, experimental data to explain the non-pregnant and benign patients with or without this hormone in the blood; cancer patients with hCG is higher than benign disease patients; cancer patients with hCG levels of surgery, chemotherapy and radiotherapy and other treatment sensitivity; As well as the hypothesis of whether to prove the non-gestational and non-neoplastic origin of hCG. MATERIAL AND METHODS: Serum samples were obtained from 18 cases of endometrial carcinoma, 17 cases of ovarian adenocarcinoma and 34 cases of benign gynecological diseases (including uterine fibroids and ovarian cysts, etc.); ascites samples were taken from 9 cases of ovarian cancer patients; ovarian cysts Fluid from 14 cases of benign ovarian cysts. In addition, 30 individuals with pituitary gland taken from non-tumor non-pregnant subjects.