四君子汤联合常规放疗治疗食管癌随机平行对照研究

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[目的]观察四君子汤联合常规放疗治疗食管癌疗效。[方法]使用随机平行对照方法,将80例住院及门诊患者按随机数字表法分为两组。对照组40例常规放疗治疗。治疗组40例四君子汤(人参去芦10g,白术、茯苓去皮各9g、甘草炙6g),研磨成细末药用15g,1剂/d,早晚口服;常规放疗治疗同对照组。连续治疗14d为1疗程。观测临床症状、病灶直径、不良反应。连续治疗4疗程,判定疗效。随访半年,观测满意度。[结果]治疗组CR10例,PR15例,SD10例,PD5例,总有效率62.50%。对照组CR5例,PR10例,SD11例,PD14例,总有效率37.50%。治疗组疗效优于对照组(P<0.05)。[结论]四君子汤联合常规放疗治疗食管癌效果显著,值得推广。 [Objective] To observe the curative effect of Sijunzi Decoction combined with conventional radiotherapy on esophageal cancer. [Methods] Using randomized parallel method, 80 inpatients and outpatients were divided into two groups according to random number table. Control group 40 cases of conventional radiotherapy. Treatment group 40 Sijunzi Decoction (ginseng to reed 10g, Atractylodes, Poria cortex each 9g, licorice Sunburn 6g), ground into a fine medicinal 15g, 1 / d, morning and evening oral; conventional radiotherapy treatment with the control group. Continuous treatment 14d for a course of treatment. Observation of clinical symptoms, lesion diameter, adverse reactions. Continuous treatment of 4 courses to determine the efficacy. Follow-up six months, observation satisfaction. [Results] The treatment group CR10 cases, PR15 cases, SD10 cases, PD5 cases, the total effective rate was 62.50%. Control group CR5 cases, PR10 cases, SD11 cases, PD14 cases, the total effective rate was 37.50%. The treatment group was better than the control group (P <0.05). [Conclusion] Sijunzitang combined with conventional radiotherapy has a significant effect on esophageal cancer and is worth promoting.
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