Expression of p53 and CD44 in Canine Breast Tumor

• 作 者: LIU Yun CUI Wen CHENG Xi FENG Xinchang
• 机 构: College of Veterinary Medicine,Northeast Agricultural University,Harbin 150030,China
• 出 处: 东北农业大学学报（英文版）
• 发表日期: 2008年3期
• 关键词: canine breast tumor p53 CD44

The p53 and CD44 expression of 10 cases in canine breast tumor were examined utilizing immunohistochemical assay with rabbit anti-mouse polyclonal antibodies against p53 or CD44,respectively.The p53 expression was significantly higher in malignant than in benign breast tumor.The expression of CD44 was not significantly different in malignant breast cancer and benign breast tumor.This suggests that p53 can be used as an indicator for animal prognosis.