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目前已明确,人乳头瘤病毒(HPV)高危型持续感染是宫颈上皮内瘤变(CIN)和宫颈癌发生的必要因素。从宫颈感染高危型HPV(HR-HPV)至发展成为宫颈癌通常需要8~15年,其间要经历漫长的癌前病变过程[1],故完全可通过普查和早期治疗来防治宫颈癌。临床上,宫颈高度病变(CINⅡ、CINⅢ)进一步向侵润癌发展的风险远高于低度病变(CINⅠ),低度病变大部分则自行消退或逆转[2]。因此,宫颈高度病变的早期发现、早期诊断
It has been clear that high-risk type of human papillomavirus (HPV) persistent infection is a necessary factor for cervical intraepithelial neoplasia (CIN) and cervical cancer. Cervical cancer from high-risk HPV (HR-HPV) to develop into cervical cancer usually takes 8 to 15 years, during which to go through a long process of precancerous lesions [1], so completely through census and early treatment to control cervical cancer. Clinically, cervical lesions (CIN II, CIN III) further develop the risk of invasive cancer is much higher than low-grade lesions (CIN Ⅰ), most of the low-grade lesions subside or reverse themselves [2]. Therefore, early detection of cervical lesions, early diagnosis