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目的分析冠心病患者血液检验相关指标检测的意义。方法 40例冠心病患者作为冠心病组,同期进行体检的20例健康人作为对照组,对两组研究对象的血小板相关参数、心肌标志物水平进行比较。结果冠心病组中心绞痛、急性心肌梗死患者的红细胞分布宽度(RDW)(13.78±0.73)%、(14.10±1.41)%均高于对照组(13.08±0.51)%,急性心肌梗死患者的RDW高于心绞痛患者,差异均具有统计学意义(P<0.05);心绞痛、急性心肌梗死患者和对照组的血小板计数(PLT)、血小板压积(PCT)、血小板平均体积(MPV)、血小板分布宽度(PDW)比较,差异无统计学意义(P>0.05)。冠心病组中心绞痛、急性心肌梗死患者的心肌肌钙蛋白I(cTnI)、心肌肌钙蛋白T(cTnT)、高敏心肌肌钙蛋白T(hs-cTnT)、肌酸激酶同工酶(CK-MB)水平均高于对照组,急性心肌梗死患者的cTnI、cTnT、hs-cTnT、CK-MB水平高于心绞痛患者,差异均具有统计学意义(P<0.05)。结论冠心病患者血液检验相关指标中RDW增大会在一定程度上影响患者预后,cTnI水平提升标志着患者心肌损伤。
Objective To analyze the significance of blood test related indexes in patients with coronary heart disease. Methods Twenty patients with coronary heart disease (CHD) were enrolled in this study. Twenty healthy subjects who underwent physical examination during the same period were taken as control group. The platelet-related parameters and myocardial markers were compared between the two groups. Results The distributions of RDW (13.78 ± 0.73)% and (14.10 ± 1.41)% in patients with coronary heart disease and acute myocardial infarction were significantly higher than those in the control group (13.08 ± 0.51%). The RDW in patients with acute myocardial infarction (P <0.05). PLT, PCT, MPV and platelet distribution width in patients with angina pectoris, acute myocardial infarction and control group were significantly higher than those in control group PDW), the difference was not statistically significant (P> 0.05). Cardiac troponin I, cTnT, hs-cTnT, CK-a and cTnT in patients with coronary heart disease and angina pectoris, acute myocardial infarction, MB) were higher than those in the control group. The levels of cTnI, cTnT, hs-cTnT and CK-MB in patients with acute myocardial infarction were significantly higher than those in patients with angina pectoris (P <0.05). Conclusion The increase of RDW in blood test-related indicators of coronary heart disease patients will affect the prognosis of patients to a certain extent. The increase of cTnI level marks the myocardial injury in patients.