论文部分内容阅读
目的观察盐酸米诺环素软膏联合甲硝唑治疗牙周炎的临床疗效。方法选择2010年2月—2011年12月收治的66例牙周炎患者,随机分为治疗组和对照组各33例,治疗组采用盐酸米诺环素软膏联合甲硝唑治疗,对照组单独使用甲硝唑治疗,两组均治疗4周后比较患者的菌斑指数、牙周袋探诊深度、附着丧失及牙龈出血指数。结果治疗组总有效率为93.94%,显著高于对照组的78.79%(P<0.05);两组治疗后比治疗前各指标均有所降低(均P<0.05)。结论盐酸米诺环素软膏联合甲硝唑治疗牙周炎效果优于单独使用甲硝唑。
Objective To observe the clinical efficacy of minocycline hydrochloride combined with metronidazole in the treatment of periodontitis. Methods Sixty-six patients with periodontitis who were admitted from February 2010 to December 2011 were randomly divided into treatment group (33 cases) and control group (33 cases). The treatment group was treated with minocycline hydrochloride combined with metronidazole, while the control group alone The patients were treated with metronidazole. The plaque index, depth of probing, attachment loss and gingival bleeding index were compared between the two groups after 4 weeks of treatment. Results The total effective rate in the treatment group was 93.94%, which was significantly higher than that in the control group (78.79%, P <0.05). The indexes in both groups were lower than those before treatment (all P <0.05). Conclusion Minocycline hydrochloride ointment combined with metronidazole treatment of periodontitis is better than metronidazole alone.