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炎症性肠病(IBD)是指原因不明的一组非特异性肠道炎症,包括溃疡性结肠炎(UC)和克罗恩病(CD)。目前,关于IBD的病因及发病机制尚未明确,一般认为可能与免疫、感染、遗传和精神等因素有关。近年来关于血清免疫特异性抗体标记物的研究较多,这些抗体包括抗中性粒细胞抗体(ANCA)、抗酿酒酵母抗体(ASCA)以及抗细菌抗原抗体等。本文通过查阅国内外文献就IBD血清学标志物的研究作一综述。
Inflammatory bowel disease (IBD) refers to a group of unexplained sets of non-specific intestinal inflammatory diseases, including ulcerative colitis (UC) and Crohn’s disease (CD). At present, the etiology and pathogenesis of IBD is not yet clear, and it is generally believed that it may be related to factors such as immunity, infection, heredity and spirit. In recent years, there have been many studies on serum immunospecific antibody markers, including anti-neutrophil antibody (ANCA), anti-Saccharomyces cerevisiae antibody (ASCA), anti-bacterial antigen antibody and the like. This article reviews the literature on IBD serological markers of IBD.