Pin Down Sources for New Hepatocytes by Tracing Proliferating Cells

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Cell proliferation.one cell divides into two cells.is the basis for a fertilized egg to grow into a fetus.It is also the reason why a wound can heal itself,or a salamander can regrow its tail.When cell proliferation goes crazy,it is most likely that a cancer is being hatched.rnThe ability to monitor cell proliferation is therefore essential for a myriad of studies in developmental biology.regenerative medicine,and oncology.Therefore.scientists have put many efforts in developing different approaches for proliferation tracing.However,the limitations of current approaches for measuring cell proliferation in vivo have left many fund a mental questions in numerous life science fields insufficiently addressed.Applying these approaches to probe in vivo cell sources for tissue homeostasis and repair is,most of times,like“the blind men feeling an elephant”.The inherent bias could easily lead to conflicting conclusions,as illustrated by the highly controversial studies around cell sources for hepatocyte generation.
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