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我们用前列腺素E_1和大黄治疗失代偿期肝硬化15例,疗效明显。现报告如下。 材料和方法 1.一般情况 30例病人均符合1990年上海会议的诊断标准,按同期随机抽样原则分成两组。治疗组15例,其中男11例,女4例;年龄25~65岁,病程3月~20年;腹水7例,脾大5例,肝肾综合征3例。对照组15例,其中男10例,女5例;年龄24~63岁,病程2月~18年;腹水6例,脾大5例,肝肾综合征4例。两组病情相似,具有可比性。 2.治疗方法 对照组采用护肝、纠正水电解质紊乱、防治感染等治疗。治疗组在此基础上加用前列腺素E_1和生大黄。方法为前列腺素E_10.1mg加入10%葡萄糖250ml/日静滴,20滴/分;生大黄50g加水100ml,煎熬5~10分钟后顿服,日1次。连续用药15天。
We use prostaglandin E_1 and rhubarb in the treatment of decompensated cirrhosis in 15 cases, the effect is obvious. The report is as follows. Materials and methods 1. General 30 patients were in line with the diagnostic criteria of the Shanghai Conference in 1990, according to the same period of random sampling principle is divided into two groups. The treatment group of 15 patients, including 11 males and 4 females; aged 25 to 65 years, duration of 3 months to 20 years; ascites in 7 cases, splenomegaly in 5 cases, liver and kidney syndrome in 3 cases. The control group of 15 patients, including 10 males and 5 females; aged 24 to 63 years, duration of 2 months to 18 years; 6 cases of ascites, splenomegaly in 5 cases, liver and kidney syndrome in 4 cases. Two groups of similar conditions, comparable. 2. Treatment of the control group using liver protection, water and electrolyte disorders to correct, control of infection and other treatment. Treatment group on this basis with prostaglandin E_1 and rhubarb. Method for the prostaglandin E_10.1mg 10% glucose 250ml / day intravenous infusion, 20 drops / min; rhubarb 50g water 100ml, 5 to 10 minutes after suffering Dayton clothing, day 1. Continuous medication for 15 days.