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目的 探讨前列地尔对重度黄症肝炎的疗效。方法 将68例重度黄疸患者随机分为两组。前列地尔35例,对照组33例。在促肝细胞生长素120mg静脉点滴的基础上,治疗组加用前列地尔注射液10ug,对照组加用门冬氨酸钾镁注射液30ml治疗,两组药物均溶于5%葡萄糖液250ml中静滴,每日1次,疗程均为4周。结果 治疗组对重度黄疽肝炎的疗效优于对照组(P<0.005),其血清胆红素的降低显著优于对照组(P<0.001)。结论前列地尔对重度黄疽肝炎有明确疗效。
Objective To investigate the curative effect of alprostadil on severe yellow hepatitis. Methods Sixty-eight patients with severe jaundice were randomly divided into two groups. Alprostadil 35 cases, control group 33 cases. In the promotion of hepatotrophic hormone 120mg intravenous drip on the basis of the treatment group with alprostadil 10ug, the control group plus aspartate potassium magnesium injection 30ml treatment, the two groups of drugs were dissolved in 5% glucose solution 250ml In intravenous infusion, 1 day, treatment are 4 weeks. Results The curative effect of the treatment group on severe jaundice hepatitis was better than that of the control group (P <0.005). The reduction of serum bilirubin was significantly better than that of the control group (P <0.001). Conclusion Alprostadil has a clear effect on severe jaundice hepatitis.