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对１４例肠病相关的Ｔ细胞性淋巴瘤（ＥＡＴＣＬ）进行临床和病理分析，并对其免疫表型进行研究。结果显示：临床上ＥＡＴＣＬ多见于青壮年男性，常有发热、贫血、慢性腹痛、腹泻及便血，半数以上病例在病程中出现肠穿孔；３系细胞减少，肝脾肿大，浅表淋巴结肿大较少见。病理上以回、结肠多发溃疡为特征，无肿块形成；镜下为异型淋巴细胞散在浸润，常有大片坏死，肠粘膜萎缩，血管浸润及嗜上皮现象；单核组织细胞反应明显常为其特点之一。免疫组化标记１４例均为Ｔ细胞阳性。文中对如何从临床和病理上提高ＥＡＴＣＬ的诊断率进行了讨论。另外，本研究发现在ＨＥ切片中有明显吞噬功能的组织细胞样细胞其免疫标记也为Ｔ细胞阳性。
Clinical and pathological analysis was performed on 14 cases of enterocyte-associated T-cell lymphoma (EATCL) and its immunophenotype was studied. The results showed that: Clinical EATCL more common in young men, often have fever, anemia, chronic abdominal pain, diarrhea and bloody stools, more than half of the cases in the course of intestinal perforation; 3 lines of cell reduction, hepatosplenomegaly, superficial lymphadenopathy Less common. Pathologically, it is characterized by multiple ulcers in the gyrus and colon. No lumps are formed. Microscopic lymphocytes are scattered and infiltrated. There are often large necrotic areas, intestinal mucosal atrophy, vascular infiltrates, and epithelial cells. Mononuclear histiocytic cells are often characterized by histological features. one. Fourteen immunohistochemical markers were positive for T cells. The article discusses how to improve the diagnostic rate of EATCL clinically and pathologically. In addition, this study found that histologically cell-like cells with phagocytosis in HE sections were also positive for T cells.