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目的了解襄阳市襄州区健康成人麻疹抗体水平,为消除麻疹提供参考。方法 2013年5-6月,按照《湖北省健康成人麻疹抗体水平监测方案》规定的抽样方法,选定襄州区15~19岁、20~24岁、25~29岁、30~34岁以及35岁以上5个年龄组798名健康成人进行个案调查和采集血液标本,用酶联免疫吸附试验检测麻疹抗体。结果麻疹抗体阳性率为87.34%,几何平均滴度为1∶552.04;麻疹抗体保护率为22.56%。不同年龄、性别和职业的麻疹抗体阳性率差异均无统计学意义(P>0.05);而麻疹抗体保护率则存在差异,30岁以下、学生、女性相对较低。结论襄州区成人麻疹抗体阳性率相对较高,而麻疹抗体保护率则较低,难以形成牢固的保护屏障。建议增加成人麻疹疫苗接种,提高成人麻疹免疫水平,降低麻疹发病率。
Objective To understand the level of measles antibody in healthy adults in Xiangzhou District, Xiangyang City, so as to provide reference for eliminating measles. Methods From May to June 2013, according to the sampling method stipulated in the “Monitoring Program of Measles Antibody Level of Healthy Adults in Hubei Province”, the sampling method was selected in Xiangzhou District from 15 to 19 years old, 20 to 24 years old, 25 to 29 years old, 30 to 34 years old and A total of 798 healthy adults in 5 age groups over 35 years old were investigated for the case and blood samples were collected. The measles antibody was detected by enzyme linked immunosorbent assay. Results The positive rate of measles antibody was 87.34%. The geometric mean titer was 1: 552.04. The measles antibody protection rate was 22.56%. There were no significant differences in the positive rates of measles antibody among different ages, sexes and occupations (P> 0.05). However, the antibody protection rates of measles were different. Under 30, students and females were relatively low. Conclusion The positive rate of adult measles antibody in Xiangzhou District is relatively high, while the protective rate of measles antibody is low, which makes it difficult to form a solid protective barrier. It is recommended to increase adult measles vaccination, raise the level of adult measles immunity and reduce the incidence of measles.