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目的 :评价洛赛克和德诺三联疗法对治疗幽门螺旋杆菌感染的疗效。方法 :64例幽门螺旋杆菌感染患者随机分为两组 ,分别给予洛赛克 ( 2 0mg ,每日二次 )和德诺 ( 2 4 0mg ,每日二次 )三联疗法治疗 ,疗程为两周 ,测定治疗前后的IB(IntensityoverBaseline)值 ,并对两种疗法治疗前后的疗效进行比较。结果 :洛赛克三联疗法治疗后总有效率为 88 9% ,德诺三联疗法治疗后总有效率为75 0 %。结论 :洛赛克及德诺三联疗法治疗幽门螺旋杆菌感染均有效 ,但前者优于后者。
OBJECTIVE: To evaluate the efficacy of triple therapy with Losec and Deno in the treatment of Helicobacter pylori infection. Methods: Sixty-four patients with Helicobacter pylori infection were randomly divided into two groups. The patients were treated with three groups of Losec (20 mg twice daily) and Deno (240 mg twice daily) for two weeks , Before and after treatment of the determination of IB (Intensity over Baseline) value, and the efficacy of the two treatments before and after treatment were compared. Results: The total effective rate was 88 9% after the triple therapy of Losec and 75 0% after the treatment of de novo triple therapy. Conclusion: Both Losec and Deno triple therapy are effective in treating H. pylori infection, but the former is better than the latter.