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对51名男性和26名女性铬作业工人尿NAG活性进行了研究。在铬作业工人中,当受检者尿蛋白和尿β2-MG均处于正常范围内时,尿NAG活性已开始显著高于对照组。随着肾损害程度的加重,尿NAG活性亦呈显著性升高,并与尿蛋白及尿β2-MG呈显著性相关。结果提示,尿NAG可作为铬性肾损害的早期敏感的监测指标
The urinary NAG activity of 51 male and 26 female chrome workers was studied. Among chromium workers, urinary NAG activity began to be significantly higher than that of the control subjects when both urinary protein and urinary β2-MG were in the normal range. With the aggravation of renal injury, urinary NAG activity also showed a significant increase, and with urinary protein and urinary β2-MG was significantly related. The results suggest that urinary NAG can be used as an early sensitive indicator of chrome nephropathy