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目的:探讨血浆D—D及高敏C反应蛋白(hs—CRP)在妊娠高血压综合征患者血清中的检测及意义。方法:选择2011年9月~2012年9月在我院住院妊高征患者50例,其中子痫前期15例,轻度子痫22例,重度子痫13例,同期妊娠晚期健康妇女30例作为对照组。以免疫比浊法检测血浆D—D及hs—CRP水平。结果:实验组血浆D—D、CRP水平均高于对照组(P<0.01),轻度子痫、重度子痫患者血浆D—D及hs—CRp水平高于子痫前期患者(P<0.05),重度子痫高于轻度子痫患者(P<0.05)。CRP与D-D水平呈正相关,r=0.61,P<0.01。结论:D—D、CRP均参与了妊娠高血压综合征的发病进程,二者在妊娠高血压综合征患者中明显升高,并与疾病严重程度呈正相关。
Objective: To investigate the detection of plasma D-D and high-sensitivity C-reactive protein (hs-CRP) in serum of patients with pregnancy induced hypertension. Methods: From September 2011 to September 2012, 50 patients with PIH were hospitalized in our hospital, including 15 cases of preeclampsia, 22 cases of mild eclampsia, 13 cases of severe eclampsia and 30 cases of healthy women in the same period of pregnancy As a control group. Plasma immunoglobulin D-D and hs-CRP levels were measured by immunoturbidimetry. Results: The plasma levels of D-D and CRP in the experimental group were significantly higher than those in the control group (P <0.01). The levels of plasma D-D and hs-CRp in patients with mild eclampsia and severe eclampsia were significantly higher than those in the preeclampsia patients ), Severe eclampsia than mild eclampsia (P <0.05). CRP and D-D levels were positively correlated, r = 0.61, P <0.01. Conclusion: Both D-D and CRP are involved in the pathogenesis of pregnancy-induced hypertension syndrome. Both of them are significantly elevated in patients with pregnancy-induced hypertension and positively correlated with the severity of the disease.