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克山病具有家族多发现象,有家族发病史者约占30％。笔者收集1976—1980年符合全国诊断标准、资料完整的130例彝族小儿住院确诊克山病病例,进行家系调查。先证者130例中,男62例,女68例,年龄1—15岁,双亲均为彝族农民。有家族史者38例,占29.23％,其中“垂直”家族发病者16例,“平行”家族发病者12例,既有“垂直”又有“平行”谱系发病者10例,分别占42.1％、31.6％和26.3％。典型家系见图1、图2。
Keshan disease with multiple family phenomenon, a history of family history of about 30%. The author collected from 1976 to 1980 in line with the national diagnostic criteria, complete information of 130 cases of Yi children diagnosed Keshan disease cases, pedigree investigation. Among the 130 cases of probands, 62 were male and 68 were female, aged from 1 to 15 years old. Both parents were Yi peasants. There were 38 cases with family history, accounting for 29.23%. There were 16 cases of “vertical” family onset and 12 cases of “parallel” family. There were 10 cases of both “vertical” and “parallel” pedigree, accounting for 42.1% , 31.6% and 26.3% respectively. A typical family see Figure 1, Figure 2.