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目的总结手足口病患儿的临床特征,并分析易诱发儿童手足口病的危险因素。方法抽取2012年12月-2014年4月在浙江省台州市第一人民医院进行治疗的182例手足口病患儿作为观察组,另选68例健康儿童作为对照组。两组儿童特征进行比较,总结手足口病患儿的临床特征,并用Logistic回归方法分析手足口病的危险因素。结果手足口病患儿以轻型病症为主,临床主要表现为发热(87.9%)、口痛(86.4%)、厌食(76.2%)、口腔黏膜出现散在疱疹或溃疡(64.1%)为主;玩具定期消毒(OR=0.357)、养宠物(OR=2.241)、类似症状者接触史(OR=2.667)、公共设施接触史(OR=2.833)、卫生习惯(OR=1.033)和家长对手足口病的了解情况(OR=2.021)与手足口病的发生具有相关性(P<0.05)。结论手足口病患儿临床特征为发热、流涕、口痛、厌食、口腔黏膜出现散在疱疹或溃疡为主;而玩具不定期消毒、养宠物、与类似症状者接触、公共设施接触、不良卫生习惯和家长对手足口病的不了解是手足口病的危险因素。
Objective To summarize the clinical features of children with hand-foot-mouth disease and to analyze the risk factors of hand-foot-mouth disease in children. Methods A total of 182 HFMD children treated in the First People’s Hospital of Taizhou, Zhejiang Province from December 2012 to April 2014 were selected as the observation group and 68 healthy children were selected as the control group. The characteristics of two groups of children were compared, the clinical features of children with HFMD were summarized, and the risk factors of HFMD were analyzed by Logistic regression. Results The patients with hand-foot-mouth disease were mainly mild type. The main clinical manifestations were fever (87.9%), stomatitis (86.4%), anorexia (76.2%) and herpes simplex or ulceration (64.1%) in oral mucosa. (OR = 0.357), pets (OR = 2.241), history of similar symptoms (OR = 2.667), history of public facility exposure (OR = 2.833), hygiene (OR = 1.033), and parental HFMD (OR = 2.021) was associated with the occurrence of HFMD (P <0.05). Conclusion The clinical features of children with HFMD are fever, runny nose, mouth pain, anorexia and herpes simplexis or ulceration in oral mucosa. However, toys are not regularly disinfected, pets are kept in contact with similar symptoms, public facilities are exposed, and poor hygiene Habitual and parental HFMD do not understand HFMD risk factors.