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铁在人体代谢中是一个非常重要的元素。它不仅在红细胞生成中具有重要作用,而且在人体所有组织中参与许多细胞内代谢过程。近年,有关铁的正常生理过程人们有了不少新认识。本文将概述铁的生物化学及其在体内转运的最新看法。铁的转运一、细胞外铁的转运血浆转铁蛋白: 外环境中金属铁总是以不溶性氢氧化物存在,为了从外环境获得铁,有机体不得不形成特殊的结合铁以便其转运和贮存铁。在微生物中,铁与羟肟酸盐或儿茶酚酸盐形成了简单的
Iron is a very important element in human metabolism. It not only plays an important role in erythropoiesis, but also participates in many intracellular metabolic processes in all tissues of the body. In recent years, there have been many new understandings about the normal physiological processes of iron. This article will outline the latest biochemical insights into iron and its transport in the body. Transport of iron I. Transfer of extracellular iron Plasma transferrin: In the external environment, metallic iron is always present as an insoluble hydroxide. To obtain iron from the external environment, the organism has to form a special bound iron for its transport and storage . In microorganisms, iron forms a simple form with hydroxamates or catechins