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目的 动态观察山东省克山病病情及发病相关因素的变化。方法 选择克山病病区莒县龙山和平邑县流峪设立 2个监测点 ,对 3～ 14岁人群及 14岁以上可疑患者 14 88人为重点监测对象 ,从 1995— 1999年 ,对克山病发病情况及 2个点区县急型、亚急型、慢型克山病病情变化进行连续 5年监测 ,同时调查内外环境硒、经济收入及人均占有粮食。结果 2个点区县 5年间慢型克山病发现 1例 ,无急型、亚急型克山病发病 ,监测点重点监测对象 1995、1997、1999年克山病检出率依次为 1.81% ,2 .90 % ,2 .32 % ;异常心电图检出率为 4 .84 % ,5 .0 5 % ,5 .11% ;内环境发硒水平逐年升高 ,为 0 .2 78,0 .334,0 .36 0 mg/kg;外环境小麦硒含量稳定 ,龙山点玉米硒含量及流峪点玉米、瓜干硒含量升高 ;经济收入、人均占有粮食不断增加。结论 山东省克山病发病相关因素不断改善 ,克山病病情处于基本控制后的稳定态势
Objective To observe the changes of Keshan disease and related factors in Shandong province. Methods Two monitoring sites were set up in Liuyong, Pingyi County, Keshan County, Keshan Disease Area, and 14 88 people aged from 3 to 14 years and suspicious patients over the age of 14 were investigated. From 1995 to 1999, And the incidence of acute and subacute type and slow type Keshan disease in two county districts for five consecutive years. Meanwhile, the selenium in domestic and foreign environment, economic income and grain per capita were investigated. Results One case of chronic Keshan disease was found in two districts and counties in five years without acute and subacute Keshan disease. The key surveillance subjects of monitoring point in 1995 were 1995, 1997 and 1999, the detection rates of Keshan disease were 1.81% , 2.90% and 2.32% respectively. The detection rate of abnormal ECG was 4.84%, 5.05% and 5.111%. The selenium level in the internal environment increased year by year to 0.278.0. 334,0. 36 0 mg / kg. The selenium content of wheat in external environment was stable. The selenium content of Longshan point corn and the selenium content of corn and melon in Liuyuyu point increased. The economic income and grain per capita increased continuously. Conclusion The related factors of Keshan disease in Shandong Province have been continuously improved. The condition of Keshan disease is in a stable state after basic control