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作者以慢性肝炎、肝硬化患者为对象,进行了血浆环-磷酸腺苷(cAMP)和环-磷酸乌苷(cGMP)变化的对比观察.健康成年男子空腹时的cAMP浓度为17.94±1.36p mol/ml;慢性肝炎稳定期为28.10±2.3p mol/ml(P<0.005);慢性肝炎活动期为30.10±1.80p mol/ml(P<0.001);肝硬化为32.30±1.90p mol/ml(P<0.001).提示了这类肝疾患血浆cAMP浓度比正常人明显上升.健康成年男子
The author compared the changes of cAMP and cGMP in patients with chronic hepatitis and cirrhosis.The fasting cAMP concentration of healthy adult men was 17.94 ± 1.36p mol / ml; chronic hepatitis was 28.10 ± 2.3p mol / ml (P <0.005); chronic hepatitis activity was 30.10 ± 1.80p mol / ml (P <0.001); cirrhosis was 32.30 ± 1.90p mol / ml P <0.001), suggesting that this type of liver disease plasma cAMP concentration was significantly higher than normal. Healthy adult men