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反复呼吸道感染(RRTI)是儿科常见病,近年发现Ig G亚类缺陷是其重要发病原因。缺铁缺锌亦易引起反复感染。但补充铁锌对RRTI血清Ig G亚类及T细胞功能是否有影响,尚不清楚。为探讨微量元素-感染-免疫三者间关系,本文对34例伴有血清铁和/或锌水平降低的RRTI患儿进行了口服富马酸亚铁(元素铁4.5~6mg/kg·d~(-1))和/或硫酸锌(2~4mg/kg·d~(-1))治疗前后的对比观察。结果表明补充铁和/或锌2个月后,随血清铁、锌水平恢复正
Recurrent respiratory tract infections (RRTI) is a common pediatric disease, in recent years found Ig G subtype defects is its important pathogenesis. Iron deficiency zinc deficiency can cause repeated infections. However, iron and zinc supplementation of RRTI serum Ig G subtypes and T cell function whether or not affected, it is not clear. In order to explore the relationship between trace elements-infection-immunity, 34 patients with RRTI with reduced serum iron and / or zinc levels were treated with oral ferrous fumarate (4.5-6 mg / kg · d ~ (-1)) and / or zinc sulfate (2 ~ 4mg / kg · d ~ (-1)) before and after treatment. The results showed that with iron and / or zinc supplementation two months later, with serum iron, zinc levels returned to positive