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目的观察缬沙坦降低早期糖尿病肾病(DN)尿微量白蛋白的临床疗效。方法选择60例早期糖尿病肾病患者,比较未治疗前与加用缬沙坦治疗后3、6个月24h尿蛋白定量。结果治疗后3、6个月患者24h尿蛋白定量均有显著下降(P<0.05)。结论尽早使用ARB治疗可以延缓糖尿病早期肾病的进展。
Objective To observe the clinical efficacy of valsartan in reducing diabetic microalbuminuria in patients with early diabetic nephropathy (DN). Methods Sixty patients with early diabetic nephropathy were enrolled, and the urinary protein excretion was compared 24h and 36h after treatment with valsartan. Results The urinary protein excretion of 24 hours after treatment was significantly decreased (P <0.05). Conclusion Early treatment with ARB can delay the progression of early diabetic nephropathy.