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目的:观察益髓补肾方对恶性血液病患者围化疗期生活质量的影响。方法:选取100例恶性血液病患者作为研究对象,按照随机数字法分为益髓补肾方组及对照组,各50例,益髓补肾方组在围化疗期给予益髓补肾方+化疗治疗,对照组在围化疗期给予单纯化疗,在一疗程的化疗结束后以问卷形式行生活质量的评估,共计4个疗程。结果:益髓补肾方组患者总有效率均优于对照组(44.00%/30.00%),不良反应的发生率低于对照组(30.00%/60.00%),差异均有统计学意义(P<0.05);治疗后,益髓补肾方组患者总体健康状况、功能量表各项评分均高于对照组(P<0.05);症状量表各项目评分均低于对照组(P<0.05);六个单项测量项目除经济困难外,益髓补肾方组各指标评分均低于对照组(P<0.05)。结论:益髓补肾方联合化疗治疗HM患者效果显著,可有效提高其治疗后的生活质量,值得借鉴和推广。
Objective: To observe the effect of Yisu Bushen Decoction on quality of life of patients with hematologic malignancies in perioperative chemotherapy. Methods: 100 cases of hematologic malignancies were selected as research objects. According to the random number method, 50 cases were divided into Yishen Bushenfang group and control group, and each group of Yishen Bushenfang treated with Yishen Bushenfang + The control group received chemotherapy alone during the chemotherapy period. After a course of chemotherapy, quality of life was assessed by questionnaire, for a total of 4 courses. Results: The total effective rate of Yishen Bushen Recipe group was better than that of control group (44.00% / 30.00%), the incidence of adverse reactions was lower than that of control group (30.00% / 60.00%), the differences were statistically significant (P < 0.05). After treatment, the scores of general health status and functional scale of Yishen Bushen Recipe group were higher than those of control group (P <0.05). The score of each symptom scale was lower than that of control group (P <0.05). In addition to the economic difficulties, the six individual measurement items were significantly lower than those of the control group (P <0.05). Conclusion: Yishen Bushen Recipe combined with chemotherapy has significant effect on patients with HM, which can effectively improve the quality of life after treatment. It is worth learning from and promoting.