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本文抽查我院1995年01至12月份3525例住院病案,对抗生素使用及医院感染情况进行了调查分析。我院抗生素应用32种,平均15.7天,使用率81.9%,Ⅰ联33.4%、Ⅱ联46.2%、Ⅲ联20.7%、Ⅳ联5.6%,预防用药18.4%,手术操作预防用药34.9%,存在术前预防用药时间过早,术后预防用药停药过晚。无指征和配伍不当均属不合理用药为16.4%。抗生素的联合应用、用药配伍不当均以外科系统明显。医院感染率为3.8%,漏报率为24.8%。未用抗生素与应用抗生素者院内感染发生率无显著性差异(P>0.05),说明无指征应用抗生素预防院内感染是途劳无益,并提示院内感染随抗生素联合应用种数及住院天数延长而升高。提示要加强对医务人员医院感染和正确合理应用抗生素等有关知识的学习。
This article checks our hospital from January to December 1995 3525 cases of hospitalization, antibiotic use and hospital infection were investigated and analyzed. 32 kinds of antibiotics used in our hospital, with an average of 15.7 days, the use rate of 81.9%, I joint 33.4%, Ⅱ joint 46.2%, Ⅲ combined 20.7%, IV combined 5.6%, preventive medicine 18.4%, preventive operation 34.9% of surgical procedures, there preoperative preventive medication premature, postoperative preventive drug withdrawal too late. No indications and improper compatibility are irrational medication was 16.4%. The combination of antibiotics, drug compatibility improper surgical systems are obvious. Hospital infection rate was 3.8%, omission rate was 24.8%. There was no significant difference in the incidence of nosocomial infection between antibiotics and antibiotics (P> 0.05), indicating that no indications antibiotics to prevent nosocomial infections is unhelpful, and prompted nosocomial infections with antibiotics combined with the number of days of hospitalization Extend and rise. Tip to strengthen medical staff hospital infection and the correct and rational use of antibiotics and other related knowledge of learning.