论文部分内容阅读
目的探讨使用小剂量雌激素对诱导排卵患者的排卵以及子宫内膜发育的影响。方法选取2010年5月至2013年5月商丘市妇幼保健院收治的80例无排卵性不孕妇女,随机分为普通组和观察组,普通组40例患者只使用氯米芬促进排卵,观察组40例患者在普通组基础上加用小剂量雌激素,对卵泡发育以及子宫内膜厚度进行监测,对比两组结果。结果单使用氯米芬患者的排卵率较高,但是妊娠率较低,加用雌激素之后,两组排卵率相近,妊娠率显著提高,达到了75.09%;普通组的子宫内膜增生晚期厚度为(0.74±0.21)cm,观察组达到了(1.02±0.22)cm,两组结果对比差异有统计学意义(P<0.05)。结论雌激素与氯米芬联合使用可以促进子宫内膜生长,雌激素对排卵率没有明显影响。
Objective To investigate the effect of low dose estrogen on ovulation induction and endometrial development in induced ovulation patients. Methods 80 cases of anovulatory infertility women who were treated in Shangqiu MCH in May 2010 to May 2013 were randomly divided into general group and observation group, 40 patients in general group only used clomiphene to promote ovulation, observed Group 40 patients in the general group based on the use of small doses of estrogen, follicular development and endometrial thickness were monitored, the results of two groups were compared. Results Clopidogrel alone had higher ovulation rate but lower pregnancy rate. After adding estrogen, the ovulation rate of the two groups was similar and the pregnancy rate was significantly increased, reaching 75.09%. The average thickness of endometrial hyperplasia (0.74 ± 0.21) cm, the observation group reached (1.02 ± 0.22) cm, the difference between the two groups was statistically significant (P <0.05). Conclusion The combination of estrogen and clomiphene can promote the growth of the endometrium, and estrogen has no obvious effect on the ovulation rate.