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菊黄色素是从大花金鸡菊花序中提取的天然黄色素,其大、小鼠经口LD_(50)均大于21500mg/kg。它在小鼠体内无明显蓄积作用,对小鼠骨髓微核多染红细胞率及睾丸精原、精母细胞染色体畸变率,剂量高达11263.5mg/kg,均无明显影响。Ames试验剂量高达6257.5μg/皿,不论加S-9混合液与否,对组氨酸依赖型鼠伤寒沙门氏菌TA_(97)、TA_(98)、TA_(100)和TA_(102)四个测试菌株均无诱变活性。
Jujube yellow pigment is a kind of natural yellow pigment extracted from the flower anthurium inflorescence, its oral LD_ (50) in both large and mouse is more than 21500mg / kg. It had no significant accumulation in mice, and had no significant effect on the rate of erythrocyte erythrocytes in bone marrow and the chromosome aberration rate of spermatogonia and spermatocyte in mice. The dose was up to 11263.5mg / kg. Ames test dose up to 6257.5μg / dish, with or without adding S-9 mixture of histidine-dependent Salmonella typhimurium TA_ (97), TA_ (98), TA_ (100) and TA_ (102) Strain has no mutagenic activity.