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1986年捷克共和国在选定的区域内取消了强制性卡介苗普种。观察到的0-6岁儿童结核年感染率低于0.1％,而结核年发病率为7/10万。未接种儿童中增加的结核病例表明,接种卡介苗的保护作用为80％。 受益分析证实,接种卡介苗的优点和缺点持平。未接种儿童发生结核病的数目是如此之少,没有必要大量应用卡介苗。 不接种的重要优点是保留了结核菌素试验的流行病学和诊断价值。结素试验与预防性化疗结合仍然是使我们能够控制受感染者的重要工具。
In 1986, the Czech Republic canceled the mandatory BCG vaccination in selected areas. The observed prevalence of tuberculosis in children aged 0-6 years is less than 0.1%, compared to 7/10 in tuberculosis. Tuberculosis cases in unvaccinated children showed that the protective effect of BCG vaccination was 80%. Benefit analysis confirmed that the advantages and disadvantages of BCG vaccination were unchanged. The number of tuberculosis cases in unvaccinated children is so small that there is no need for extensive use of BCG. An important advantage of non-vaccination is the retention of the epidemiological and diagnostic value of the tuberculin test. The combination of tuberculosis test and preventive chemotherapy remains an important tool that allows us to control the infected population.