论文部分内容阅读
目的 探索大肠恶性肿瘤血液流变学及血脂水平变化的规律 ,评价其临床意义。方法 对 64例大肠恶性肿瘤、2 6例大肠息肉、3 6例普通病人检测了血液流变学指标、血甘油三酯、胆固醇、高密度脂蛋白、低密度脂蛋白、极低密度脂蛋白。结果 大肠息肉组与正常组各项指标间无明显差异 ,大肠癌有淋巴结转移及远处转移时全血中、低切粘度、血浆粘度、全血还原粘度、红细胞聚集指数、红细胞变形指数、血沉方程K值均明显增高 ,血甘油三酯、低密度脂蛋白及极低密度脂蛋白也增高。结论 随着大肠癌病情的发展 ,血脂代谢出现异常 ,血液流变学出现明显变化 ,动态观察血液流变学和血脂改变 ,对大肠癌诊治及监测有重要意义。
Objective To explore the hemorheology and changes of blood lipid levels in colorectal malignancies and evaluate their clinical significance. Methods Hemorheological parameters, blood triglyceride, cholesterol, high-density lipoprotein, low-density lipoprotein, and very low-density lipoprotein were detected in 64 cases of colorectal cancer, 26 cases of colorectal polyps, and 36 cases of normal patients. Results There was no significant difference between the indexes of colorectal polyp and normal group. The colorectal cancer had lymph node metastasis and distant metastasis, whole blood, low shear viscosity, plasma viscosity, whole blood reduced viscosity, red blood cell aggregation index, red blood cell deformability index, erythrocyte sedimentation rate The K value of the equation was significantly higher, and blood triglycerides, low-density lipoproteins, and very low-density lipoproteins were also increased. Conclusion With the development of colorectal cancer, abnormal blood lipid metabolism and obvious changes in hemorheology, dynamic observation of hemorheology and changes in blood lipids are important for the diagnosis and treatment of colorectal cancer.