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目的探讨采用盐酸特比萘芬片对真菌性皮肤病进行治疗的临床效果。方法随机选取2014年7月—2015年9月期间收治的真菌性皮肤病患者92例,所有患者均资料完整,按照入院先后顺序对其行不同治疗,其中对照组患者单用特比萘芬乳膏进行外敷治疗,观察组患者则采用特比萘芬乳膏联合盐酸特比萘芬片进行治疗,对两组患者的临床症状改善情况及其真菌清除情况进行观察分析。结果本次研究中观察组患者经治疗共91.30%临床症状和体征得到明显改善,真菌清除率为82.61%;对照组患者则为76.09%,真菌清除率为58.70%,同对照组患者相比,观察组的整体治疗效果及真菌清除率均有明显优势,差异具有显著性(P<0.05)。结论采用特比萘芬乳膏联合盐酸特比萘芬片对真菌性皮肤病进行治疗,可有效清除真菌,且不会引起患者出现严重不良反应,对于患者临床体征和症状的改善具有十分积极的意义,建议在临床上进一步推广。
Objective To investigate the clinical effect of terbinafine hydrochloride tablets in the treatment of fungal dermatosis. Methods Totally 92 patients with fungal dermatosis were selected randomly from July 2014 to September 2015. All the patients were data-complete and were treated according to the order of admission. The patients in the control group were treated with terbinafine alone Ointment for external application of treatment, the observation group was treated with terbinafine cream combined with terbinafine hydrochloride tablets for treatment of patients with clinical symptoms and fungal clearance were observed and analyzed. Results In this study, 91.30% of the patients in the observation group had significantly improved clinical symptoms and signs, the fungal clearance rate was 82.61%, that of the control group was 76.09%, and the fungal clearance rate was 58.70%. Compared with the control group, The observation group’s overall treatment effect and fungal clearance rate has obvious advantages, the difference was significant (P <0.05). Conclusions The treatment of fungal dermatosis with terbinafine cream combined with terbinafine hydrochloride tablets can effectively remove fungi without causing serious adverse reactions in patients and is very positive for clinical signs and symptoms improvement Significance, it is recommended to further promote the clinical.