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利用双抗体夹心法,检测14例轻度子宫内膜异位症不孕妇女(异位症组)和11例其他原因所致不孕妇女(对照组)腹腔液肿瘤坏死因子(TNF)和白细胞介素6(IL-6)的含量。结果显示,轻度子宫内膜异位症不孕妇女腹腔液TNF和IL-6的水平较对照组明显升高。表明腹腔液细胞因子水平升高可能参与了子宫内膜异位症不孕的发病机理。
14 patients with mild endometriosis infertility (ectopic group) and 11 other infertile women (control group) were treated with peritoneal fluid tumor necrosis factor (TNF) and leucocyte Interleukin 6 (IL-6) content. The results showed that the levels of TNF and IL-6 in peritoneal fluid of mild endometriosis infertile women were significantly higher than those in the control group. That the increase of peritoneal fluid cytokines may be involved in the pathogenesis of endometriosis infertility.