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目的:比较双胎妊娠孕产妇与正常单胎妊娠孕产妇妊娠结局的差异。方法:收集2005年9月至2009年12月97例双胎妊娠孕妇(双胎组)与100例正常单胎妊娠孕妇(对照组)的临床资料,分析比较两组妊娠期高血压疾病(PDH)、妊娠期肝内胆汁淤积症(ICP)、贫血、胎膜早破、早产、产后出血、围生儿情况及剖宫产率。结果:双胎组与对照组的PDH发生率分别为24.7%、6.0%,ICP发生率分别为7.2%、2.0%,贫血发生率分别为72%、50%,胎膜早破发生率分别为13.4%、3%,早产率分别为42.3%、3.0%,产后出血率分别为14.1%、2.0%,围产儿死亡率分别为5.2%、0%,剖宫产率分别为79.4%、41%,两组间比较差异均有统计学意义(P<0.05)。结论:双胎妊娠可以增加孕产妇的并发症及围产儿死亡率,应予以重视。
Objective: To compare the difference of pregnancy outcome between pregnant women of twin pregnancy and normal singleton pregnancy. Methods: The clinical data of 97 pregnant women with twin pregnancy (twin group) and 100 normal pregnant women with single pregnancy (control group) from September 2005 to December 2009 were collected. The prevalence of gestational hypertension (PDH ), Intrahepatic cholestasis of pregnancy (ICP), anemia, premature rupture of membranes, premature labor, postpartum hemorrhage, perinatal conditions and cesarean section rate. Results: The incidence of PDH in twins and controls were 24.7% and 6.0% respectively. The incidence of ICP was 7.2% and 2.0% respectively. The incidence of anemia was 72% and 50% respectively. The incidences of premature rupture of membranes were 13.4%, 3%, premature delivery rates were 42.3%, 3.0%, postpartum hemorrhage rates were 14.1%, 2.0%, perinatal mortality rates were 5.2%, 0%, cesarean section rates were 79.4%, 41% , The difference between the two groups was statistically significant (P <0.05). Conclusion: Twin pregnancy can increase maternal complications and perinatal mortality, which should be taken seriously.