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近年来,发现免疫抑制剂对葡萄膜炎有一定作用,本院曾对顽固、反复再发的葡萄膜炎试用环磷酰胺,收到初步效果,总结如下:患者,女,44岁,1979年2月2日入院。双眼自1971年始患葡萄膜炎,1973年左眼球萎缩。右眼9年来经常充血、疼痛,视力逐渐下降。1976～1977年因继发青光眼曾先后行3次降压术,但葡萄膜炎复发,曾多次以氢化可的松、红霉素静点。眼科检查:视力右0.02(不能矫正),睫状充血(+),角膜后大量 KP,房水混浊,虹膜纹理不清,部分色素脱失,瞳孔9点～1点虹膜缺损,但皆后粘连,晶体后囊下皮质呈褐色,玻璃体絮状混浊,眼底朦胧不清,左眼球萎缩,入院后用氢化可的松、红霉素无效。自2月22日环磷酰胺静注200毫克,隔日1
In recent years, found that immunosuppressive agents have a role in the uveitis, the hospital had refractory repeated recurrent uveitis trial of cyclophosphamide, received initial results, summarized as follows: patients, female, 44 years old, 1979 February 2 admission. His eyes had uveitis since 1971, his left atrophy in 1973. Right eye nine years often congestion, pain, visual acuity decreased. From 1976 to 1977 due to secondary glaucoma has been three times the antihypertensive surgery, but the recurrence of uveitis, has repeatedly to hydrocortisone, erythromycin static point. Eye examination: visual acuity of the right 0.02 (can not be corrected), ciliary hyperemia (+), a large number of corneal KP, aqueous humor, iris texture is not clear, part of the depigmentation, pupil 9:00 to 1:00 iris defect, but all posterior adhesion , The posterior subcapsular cortex is brown, vitreous flocculus opacity, blurred vision, left eye atrophy, admission to hydrocortisone, erythromycin invalid. Cyclophosphamide 200 mg intravenously on February 22, every other day