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目的：了解血清总胆汁酸（ＴＢＡ）和丙型肝炎（ＨＣ）感染者之间的关系。方法：对６０名ＨＣ感染者和５０名正常人的ＴＢＡ，丙氨酸转氨酶（ＡＬＴ），草酰乙酸转氨酶（ＡＳＴ）进行测定和分析。结果：６０例ＨＣ感染者中有１６例ＴＢＡ高于正常，而ＡＬＴ、ＡＳＴ各有２例、９例高于正常，且ＴＢＡ异常增加的倍数比ＡＬＴ、ＡＳＴ增高的倍数多；４９例ＡＬＴ、ＡＳＴ正常的丙型肝炎病毒（ＨＣＶ）感染者中，仍有１１例ＴＢＡ异常。结论：测定ＴＢＡ是早期诊断ＨＣＶ感染者肝细胞损害的敏感指标
Objective: To understand the relationship between serum total bile acid (TBA) and hepatitis C (HC) infection. Methods: TBA, alanine aminotransferase (ALT) and oxaloacetate aminotransferase (AST) in 60 HC-infected and 50 normal subjects were measured and analyzed. Results: TBA was higher than normal in 16 out of 60 HC patients, ALT and AST in 2 cases, and 9 cases were higher than normal. The abnormal increase of TBA was more than that of ALT and AST; 49 ALT, AST normal hepatitis C virus (HCV) infection, there are still 11 cases of TBA abnormalities. Conclusion: The determination of TBA is a sensitive indicator of early diagnosis of hepatocellular damage in HCV-infected patients